Bioinformatics Consultant (Biomarker Development)Chronomaics

United Kingdom 30-04-2023
HealthTech

Description

Hurdle is a Chronomics brand inc.

🏠Remote-first and based in either the UK 🇬🇧, Ireland 🇮🇪, Spain 🇪🇸, Germany 🇩🇪, Serbia 🇷🇸,

🧬Who we are:

Chronomics is a tech-bio company on a mission to make biology accessible and actionable to everyone.

The world is at the dawn of a ‘bio-revolution’ - with science set to transform our lives in the coming decades. And yet today, accessing biological information - and making it actionable - is complex, costly and cumbersome.

The revolution needs an engine - and we are building it. We design and deploy ‘bio-infrastructure’ across more than a dozen verticals to simplify, speed-up and scale the use of biomarkers to improve everyday decisions.

From tele-health to travel; sleep to skincare; multivitamins to managing menopause - and many others - we partner with the world’s largest and most impactful organizations, using science to transform how they diagnose, personalize and evaluate their offerings.

With global operations and hubs in the US and Europe, we’re a team that spans science, technology, supply chain, operations and commercial. We’re growing rapidly, organically and sustainably and we’re trusted by industry leaders like Superdrug, and Tui… though we’re not stopping here.

With revenue outpacing all projections and operations on three continents, we’re at a key point in our journey and we’re looking for exceptional thinkers and doers who share our mission to join us.


The role:

The Bioinformatics consultant will be responsible for maximising the biological insights we obtain from different sources of omics data, ultimately leading to the development of novel biomarker capabilities within the Chronomics bio-infrastructure that serve our partners. This is a crucial role for delivering essential Research and Development projects with big partners, combining cutting edge omics data with health insights to build and validate consumer-focused complex biomarkers of the future. Success in this role will help grow the scientific roots of Chronomics and bring novel insights, and innovation to users around the world through the wider Chronomics bio-infrastructure network. Initially this will be a 6 month contract, after completion of this time, there may be an opportunity to become a permanent employee should they demonstrate success in the role.

If you’re interested in learning more about what we do and how you could join the team, please read on and consider applying. We can’t wait to get to know you and see if there’s a fit.


As our Bioinformatics Consultant you will:

  • Produce R&D deliverables (plan and carry out analyses, reports, code, …) for Chronomics R&D partnerships (inc. pharma and life sciences partnerships) within agreed timeframes.
  • Develop analysis pipelines where necessary.
  • Present deliverables internally and to R&D partners.

Other ad hoc duties:

  • Bring expertise in other omics and multi-omics integration.
  • Develop, QC and maintain our bioinformatic pipelines.
  • Bring on-board the latest tools or software for the relevant tasks (e.g. epigenetic imputation, graph alignments, mendelian randomization, …).
  • Be able to build rapid prototypes to test out concepts quickly and cheaply
  • Write secure, scalable, documented code with automated tests.
  • Follow dev best practices
  • Document all systems

Requirements

You will be set up for success if you have:

  • PhD in Epigenetics or related field and/or 4+ years of research experience in computational biology environments.
  • Deep knowledge and expertise in DNA methylation arrays
  • Good programming skills in common bioinformatics tools such as R, Python, bash, and ideally workflow languages (e.g. Nextflow).
  • Excellent knowledge of statistical modelling and machine learning
  • Experience working with large and complex datasets including multi-omics


What would make you amazing (nice to haves):

  • Experience with Next-generation sequencing (including downstream biological annotation tools).
  • Experience working with wet-lab scientists.
  • Experience in AWS.
  • Previous experience with biomarker discovery.
  • Previous experience with a large human cohort (e.g. UK Biobank) and Electronic Health Records.
  • Knowledge in immunology/inflammation/ageing and epigenetic clocks.
  • Knowledge of epidemiological analyses (e.g. survival analysis).
  • Familiar with complex technologies (proteomics, mass spectrometry, microfluidics, imaging, …).
  • Good understanding of common molecular biology technologies (PCR, chromatography, ELISA).
  • Familiar with regulatory frameworks for IVDs.
  • Passionate about preventative healthcare.



Ideal behaviours:

  • Excellent project management skills and task-oriented.
  • Strong attention to detail.
  • Strong written and verbal communication skills (internal and external).
  • Experience communicating research outputs to scientific and broader audiences (papers, conferences, …).
  • Driven, independent and with a can-do attitude.
  • Quantitative and analytical mindset.
  • Flexibility and adaptability.
  • Thrives in a fast paced and agile environment.
  • Able to multitask and work cross functionally.
  • Resilient under pressure.
  • Creative and out-of-the-box thinking.

I&D statement
Be your authentic self at work

As we go global, we want our team to reflect the diverse and multicultural world we live in.
So, we choose to talk about Inclusion and Diversity [in that specific order] because we believe Diversity won’t be successful without Inclusion first. We build teams, cultivate leaders and create a company that’s the right fit for every person in it.
We look forward to hearing from you!

Please note, we don't accept applications from recruitment agencies - thank you!

If you’re interested in learning more about what we do and how you could join the team, please submit your application. We appreciate experience comes in different forms and you don't always need to check every box.

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Applications are now closed